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Synergistic interventions to control COVID-19: Mass testing and isolation mitigates reliance on distancing

Fig 3

Total isolations, and of those how many were individuals without symptoms (presymptomatic and asymptomatic infections), for various combined interventions.

Each dot represents an intervention combination that results in a median of 500 infections over the 30 days after intervention change (i.e., falls along the contour in Fig 2). For each intervention combination, we record the percent of all infections that are isolated while infectious (x-axis) and isolated before reporting (y-axis). Dot color represents non-pharmaceutical intervention (NPI) intensity and dot size represents test delay of the corresponding strategy. Outcomes are shown for a fixed number of test administration levels (1%, 5%, 20%, 50% of the population tested per day), and dashed lines connect strategies with the same NPI intensity across administration levels. Grey lines serve as a reference to show the percent of all isolations that occurred in those without reported symptoms. Points with cross and asterisk are discussed in the text. See S6 Fig for a version of this figure comparing results when individuals with symptomatic infections are assumed to wait for a test result to isolate.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1009518.g003