Chemotherapy-induced cachexia and model-informed dosing to preserve lean mass in cancer treatment
Fig 10
Treatment efficacy for the chemotherapy dosing schedules listed in Table 3.
(A) The AUC ratio for lean mass compares the lean mass response from the tested schedule to that of the 24 mg/kg daily schedule. (B) The AUC ratio for tumour volume compares tumour volume response from the tested schedule to that of the 24 mg/kg daily schedule. (C) The total therapeutic efficacy is the ratio of the lean mass AUC ratio to the tumour volume AUC ratio.