Chemotherapy-induced cachexia and model-informed dosing to preserve lean mass in cancer treatment
Fig 9
Treatment efficacy for the chemotherapy dosing schedules tested experimentally in [37].
(A) The AUC ratio for lean mass compares the lean mass response from the tested schedule to that of the 24 mg/kg daily schedule. (B) The AUC ratio for tumour volume compares the tumour volume response from the tested schedule to that of the 24 mg/kg daily schedule. (C) The total therapeutic efficacy is the ratio of the lean mass AUC ratio to the tumour volume AUC ratio. If a bar’s height goes above the plot, the height value is written at the top of the bar.