Chemotherapy-induced cachexia and model-informed dosing to preserve lean mass in cancer treatment
Fig 8
Treatment efficacy for the weekly dose-equivalent chemotherapy schedules listed in Table 2.
(A) The AUC ratio for lean mass compares the tested schedule to the 24 mg/kg daily schedule. (B) The AUC ratio for tumour volume compares the tested schedule to the 24 mg/kg daily schedule. (C) The total therapeutic efficacy is the ratio of the lean mass AUC ratio to the tumour volume AUC ratio.