Slipknotted and unknotted monovalent cation-proton antiporters evolved from a common ancestor
Fig 1
Schematic representation of the knotted (A) and slipknotted (B) chains.
(A) The knotted chain (left) and protein backbone (PDBID: 4kpp) (right) with a knotted core marked with blue color. This knot is called open trefoil. (B) The slipknotted chain (left) and its representation in the sodium-dependent citrate symporter (KpCitS), a protein with slipknotted backbone identified in this paper (PDBID: 5xar). The knotted core is shown in blue, the slipknot loop in orange and the slipknot tail in green.