Construction of disease-specific cytokine profiles by associating disease genes with immune responses
Table 5
Analysis of subnetworks formed by high confidence associations between the known disease associated genes and the predicted cytokines of five diseases.
The known DisGeNET genes (column #2) of a given disease often contain cytokine receptors. The number of cytokine receptors and other disease genes captured by high-confidence associations (column #3) is listed in column #4 and column #5, respectively. The number of predicted essential cytokines that interact with receptors and disease genes from DisGeNET is listed in column #6. The Immune Connection Density (ICD) estimated on the subnetworks formed by receptors, disease genes, and essential cytokines is shown in column #7.