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Construction of disease-specific cytokine profiles by associating disease genes with immune responses

Fig 8

Immune Scores of five disease classes (23 immune disorders, 48 infections, seventeen cardiovascular, thirteen metabolic, 55 neoplasms).

For each class, the average NAAS between its diseases and the cytokines within four categories are plotted: 47 inflammation related cytokines, 37 chemokines, thirteen growth factors, and 29 other cytokines. The chemokine scores for immune disorders are spread in a wide range. Growth factors have the highest scores in infections. Cardiovascular diseases have higher scores than metabolic diseases over the three groups of cytokines. Neoplasms show the lowest scores for all four categories.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1009497.g008