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Construction of disease-specific cytokine profiles by associating disease genes with immune responses

Fig 7

Cytokine features for the 171 well-studied diseases.

The 171 diseases formed three clusters based on their NASS with different types of cytokines. Immune disorders are enriched in cluster-1. Infections are split into two clusters (cluster-1 and cluster-2). Note that of the twenty neoplasms in cluster-1, nineteen are hematic and lymphatic diseases (C15/C04). Most metabolic diseases (11/13) and cardiovascular disorders (11/17) are enriched in cluster-3. Note that diseases of other classes are not counted in the labels. Cluster details are in Table D in S1 Text.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1009497.g007