Frank-Starling mechanism, fluid responsiveness, and length-dependent activation: Unravelling the multiscale behaviors with an in silico analysis
Fig 6
Half-sarcomere length LBL during a baseline heartbeat (normal hemodynamics conditions) (A). Associated attachment rate f (B) and irreversible detachment rate gd (C). These rates are used as input functions for the NO LDA model, in such a way that panels B and C also correspond to the attachment rate f and irreversible detachment rate gd for the NO LDA case.