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FunOrder: A robust and semi-automated method for the identification of essential biosynthetic genes through computational molecular co-evolution

Fig 1

Schematic representation of the lovastatin BGC from Aspergillus terreus (lov).

In red the biosynthetic genes for SM production, in gold the further essential genes, and in blue the genes not involved in the biosynthetic pathway.

doi: https://doi.org/10.1371/journal.pcbi.1009372.g001