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Hemodynamics-driven mathematical model of first and second heart sound generation

Fig 6

Relation between LV dp/dtmax and the first heart sound amplitude in simulations and reported experimental observations [26].

Conditions used in the experiment are: Aortic insufficiency, Aortic occlusion, Atropine, Artery occlusion, Epinephrine, Haemorrhage, Histamine, Isoprenaline, Methoxamine, Myocardial infarction, Norepinephrine, Phenylephrine, Pulmonary Rapid saline infusion, Pitressin, Veratridine, Venae cavae occlusion. BiVHF1-5: biventricular heart failure levels, LV dp/dt max: maximum of first derivative of left ventricular pressure, Ref: reference.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1009361.g006