Quantifying cumulative phenotypic and genomic evidence for procedural generation of metabolic network reconstructions
Fig 7
Reaction Certainty Values correlate with accurate reaction inclusion and comparison with CarveMe.
(A) The percentage of reactions identified by CANYUNs that align with the iML1515 model correlates with the associated certainty value. All reactions with a certainty value greater than or equal to 0.99 have a 94% chance of being in the iML1515 model. (B) The accuracy of discovered reactions, with inclusion in iML1515 as reference, increases with the certainty values assigned using CANYUNs. (C) Although the accuracy of the discovered reactions increases with the certainty value, there is a significant drop in the number of reactions with the increase.