Ankyrin repeats in context with human population variation
Fig 8
Comparison of the original definition of the ARD surfaces (A, B) with the new definitions derived from the results of this study (C, D). All panels refer to the D34 region of ANK1 ARD, PDB accession: 1N11 [53]. This structure shows 12 out of the 23 ARs found on this ARD; (A) Surface of an ARD. Residues conforming the concave surface are coloured in orange, residues on the convex surface in green and buried residues in blue; (B) Structure of an individual repeat. The first α-helix and the β-turn region form the concave surface, whereas the second helix and the loop form the convex one; (C) Residues forming the concave surface are coloured in dark red, residues on the convex surface in orange, the basal surface is coloured on dark green and buried residues in blue; (D) Structure of an individual repeat with new surface classification. Figure obtained with UCSF Chimera [7].