Modelling conformational state dynamics and its role on infection for SARS-CoV-2 Spike protein variants
Fig 1
N-Terminal Domain (NTD), Receptor Binding Domain (RBD), Subunit 1/Subunit 2 junction (S1/S2), Fusion Peptide (FP), Heptad Repeat 1 (HR1), Heptad Repeat 2 (HR2), Transmembrane Domain (TM), and the Cytoplasmic Tail (CT). Crystallography structure in the conformational state of all 3 RBD domains closed (PDB 6VXX) and of 1 RBD open (PDB 6VYB), binding to ACE2 (PDB 6M17).