Deep geometric representations for modeling effects of mutations on protein-protein binding affinity
Fig 4
Comparison of GeoPPI with the baseline methods in terms of prediction performance and computational speed.
(A) An example of the most conservative mutation and the predicted binding affinity changes by GeoPPI and TopGBT. (B) Prediction performance of GeoPPI and TopGBT on a subset consisting of the most conservative mutations in the S645 dataset. (C) Computational time (second/sample) needed for the prediction of individual methods.