Emergence of directional bias in tau deposition from axonal transport dynamics
Fig 5
Perturbation of initial conditions does not affect steady state.
We plot the relative pairwise error between model instances with randomly generated initial conditions using (a) the anterograde, (b) the retrograde, or (c) the net unbiased parameterizations (gray lines are representative sample traces). There is universal convergence at long time scales, suggesting that for these parameter values the model has a single fixed point.