Computational Eurotransplant kidney allocation simulations demonstrate the feasibility and benefit of T-cell epitope matching
Fig 8
(A) In ETKASPIR-F (green), the proportion of simulated transplants with a full HLA match reduces when compared to ETKAS (red). ETKASPIR-E (blue) compensates for that by maintaining the current ETKAS priority for HLA full matches. (B) PIRCHE-II scores are reduced in every HLA match group. Boxplots depict the median (horizontal line), mean (plus) and first to third quartile (box), the highest and lowest value within 1.5x IQR (whiskers), outliers (circles).