Computational Eurotransplant kidney allocation simulations demonstrate the feasibility and benefit of T-cell epitope matching
Fig 7
(A) After the simulation stabilized, the amount of cross-border donor exchange remained similar between the simulated ETKAS and ETKASPIR-E. Outliers in the burn-in period were suppressed for readability. (B) Average waiting times of transplanted patients was slightly lower in ETKASPIR-E, (C) whereas average waiting times of patients on the waiting list increased mildly. (D) number of match points given by match compatibility in the different simulations. Boxplots depict the median (horizontal line), mean (plus) and first to third quartile (box), the highest and lowest value within 1.5x IQR (whiskers), outliers (circles).