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A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes

Fig 5

AP and Ca2+ transient for adult human ventricular myocytes in the wild type case, in the SQT1 case, and in the SQT1 case with the optimal dose of each of the drugs of Table 1 applied.

The selected drugs are ordered from the smallest to the highest obtained cost function values. The applied doses are specified in Table 3. Data used in this figure can be found in S1 Data.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1009233.g005