Multi-scale simulations of the T cell receptor reveal its lipid interactions, dynamics and the arrangement of its cytoplasmic region
Fig 1
The T cell receptor structure.
(A) Model of the entire T cell receptor used in our simulations. (B) Electrostatic profile of the TCR-CD3. A range of ±5 kT/e was used to indicate the electronegative and electropositive regions as shown in red and blue respectively. The calculation of the electrostatic profile was done using the APBS tool [18].