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Relating simulation studies by provenance—Developing a family of Wnt signaling models

Fig 6

Provenance graph of all Wnt/β-catenin simulation studies considered here (black outlines) as well as additionally used studies (gray outlines).

The colors indicate the cell lines used in wet-lab experiments of that study (see legend below graph). Gray boxes represent pure Wnt/β-catenin simulation studies without acquiring wet-lab data. White boxes display publications used by some of the Wnt/β-catenin simulation studies that are either text books or simulation studies without published wet-lab data. The figure was created using the R package DiagrammeR [103]. The references to the additionally used studies are found in S1 Appendix.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1009227.g006