Relating simulation studies by provenance—Developing a family of Wnt signaling models
Fig 2
UML class diagram of provenance entities in WebProv.
We have identified the following entities to be useful for providing provenance information from simulation studies in the field of systems biology: Research Question, Assumption, Requirement, Qualitative Model, Simulation Model, Simulation Experiment, Simulation Data, and Wet-lab Data. The requested information for each entity type is kept minimal for demonstration purposes and can easily be extended. The Study (Reference) contains information of the publication, for instance, “Lee et al. (2003)” and determines which study an entity belongs to. The Description contains a brief explanation of a particular entity and may be a cited text from the publication. Furthermore, entity references should ideally consist of a digital object identifier (DOI) to make the artifact associated with the particular entity unambiguously accessible. Additional information can always be entered in the “Further Information” part of WebProv.