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Bayesian calibration, process modeling and uncertainty quantification in biotechnology

Fig 2

Relationship of independent and dependent variable.

The distribution of measurement responses (dependent variable) can be modeled as a function of the independent variable. This measurement response probability distribution (here: Student-t) is parametrized by its parameters the mean μ (solid green line) and spread parameters σ and ν. Some or all of the distributions parameters are modeled as a function of the independent variable.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1009223.g002