The unbiased estimation of the fraction of variance explained by a model
Fig 1
Sampling noise confounds estimation of the correlation between model prediction and neuronal tuning curve.
The expected (true) spike counts in response to a set of 10 stimuli (solid green points) is perfectly correlated with a model (red points), yet owing to sampling error (neural trial-to-trial variability) the estimated tuning curve (green open circles) has correlation less than one with the model ().