ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements
Fig 6
ChIP-GSM-identified TF modules at the gene promoter regions of K562 cells.
(A) Eight groups of modules identified by ChIP-GSM functioning at gene promoter regions in leukemia K562 cells (TF modules are defined in S4 Fig); (B) mRNA co-expression of pairwise TFs in each group; (C) selected modules whose target genes are significantly enriched (hypergeometric p-value < 0.001) in activated genes as shown in (D). Each color label or box represents a unique module group.