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Prioritizing and characterizing functionally relevant genes across human tissues

Fig 4

Top TRTFs capture developmental as well as structural relations among several mature tissues.

(A) Cluster dendrogram of tissues belonging to the endodermal (purple), mesodermal (green) and the ectodermal (blue) lineages. (B) Cluster dendrogram of primary and secondary reproductive organs and adipose tissue. As an illustration, we have shown for each tissue, two top TFs previously shown to be involved in the tissue development or homeostasis.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1009194.g004