Differences in olfactory bulb mitral cell spiking with ortho- and retronasal stimulation revealed by data-driven models
Fig 3
OB model captures trends in our data.
Comparison of all first and second-order statistics of coupled OB network model to our data. A) Firing rate of ortho increases and decays faster than retro in both data and model. B) Variance of spike counts for ortho and retro shown for completeness, but recall that in experimental data that they are not statistically different. C) Covariance of spike counts is larger for ortho than retro in both data and model (left), but the magnitudes of data and model differ. Comparison of the ratio of retro covariance to ortho covariance in the evoked state (right) shows that the model captures the relative differences between ortho and retro—here μ (resp. σ) is the average (resp. standard deviation) ratio over 20 time bins in the evoked state. For A–C, top shaded error regions of data (retro in A, ortho in B,C) are cut-off to better compare model and data. Comparisons of the (D) Fano factor and (E) Pearson’s spike count correlation shown for completeness despite both measures depending on spike count variance. D) The model has slightly larger Fano factor with ortho, consistent with the data. E) The model does qualitatively capture the spike count correlation for both ortho and retro, at least in the evoked state.