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Average beta burst duration profiles provide a signature of dynamical changes between the ON and OFF medication states in Parkinson’s disease

Fig 10

Simulations of average burst duration profiles for OU processes and a third degree polynomial model.

Average burst duration profiles from simulations of OU processes are compared to Eq (11) for a range of decay parameters and ζ = 1 in panel A. Similarly, average burst duration profiles from simulations of a third degree polynomial envelope model are compared to Eq (48) in panel B. Simulations are indicated by dashed lines (SEM error bars), and analytical results by dotted lines. Simulations consist of five repeats of 105 s, with a time step of 1 ms (OU process simulations use the exact updating Eq (17)).

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1009116.g010