Average beta burst duration profiles provide a signature of dynamical changes between the ON and OFF medication states in Parkinson’s disease
Fig 6
Mapping of the Wilson-Cowan model onto the STN-GPe loop.
The excitatory population E and the inhibitory population I model the basal ganglia STN and GPe, respectively. Arrows denote excitatory connections or inputs, whereas circles denote inhibitory connections or inputs. The DBS electrode is implanted in the STN (indicated by a dashed light blue line) and records the STN LFP. The STN also receives an excitatory input from the cortex, while the GPe receives an inhibitory input from the striatum, and also has a self-inhibitory loop.