Average beta burst duration profiles provide a signature of dynamical changes between the ON and OFF medication states in Parkinson’s disease
Fig 5
Sketch of burst duration metrics.
A: illustration of burst duration distance to linear surrogates in the OFF state (BDDLS OFF). BDDLS OFF is defined as the sum of squared differences between data and linear surrogate average burst duration profiles for the OFF condition divided by the square of a scale. The scale is taken as the mean value of the OFF linear surrogate average burst duration profile. BDDLS ON is defined in a similar way, and BDDLSdiff is BDDLS OFF medication minus BDDLS ON medication. B: DURdiff is defined as the sum of the differences across thresholds between burst duration profiles OFF and ON medication. In this figure, summation is indicated by the symbol +, division by the symbol /, and squaring by the symbol 2.