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From reaction kinetics to dementia: A simple dimer model of Alzheimer’s disease etiology

Fig 5

Spatial model.

A: the excess monomer production is taken to be spherically symmetric. The distance (x−axis) denotes the distance from the center of the source. The dashed circle/lines represent the boundary where excess monomer production ceases. B: monomer and dimer concentrations, and monomer production rate, versus distance from center. These values have been nondimensionalized by , , and , respectively. C: viability at various ages plotted against position.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1009114.g005