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Methodology for rigorous modeling of protein conformational changes by Rosetta using DEER distance restraints

Fig 2

Evaluation of average distances (A) and distribution widths (B) between pseudo-rotamers prior to (top) and following (bottom) refinement by multilateration. T4 lysozyme distributions omitted from multilateration are shown in light green. C and D) Boxplots showing the difference between values obtained using GLADDvu and values simulated between pseudo-rotamer ensembles prior to and following refinement.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1009107.g002