Pathway analysis in metabolomics: Recommendations for the use of over-representation analysis
Fig 3
The effect of the number of DA metabolites in the list of metabolites of interest on the number of significant pathways (p ≤ 0.1) in the Labbé et al. dataset. Results corresponding to Bonferroni thresholds are denoted by red markers while those corresponding to BH FDR thresholds are denoted by black markers. Marker shape (circle, cross, or triangle) represents the adjusted p-value threshold for DA metabolite selection (0.005, 0.05, and 0.1 respectively).