Scelestial: Fast and accurate single-cell lineage tree inference based on a Steiner tree approximation algorithm
Fig 1
Lineage trees inferred by different methods on a single-cell dataset from a muscle-invasive bladder tumor.
Nodes in these trees represent clones (i.e., inferred, evolutionary genomes ancestral to the observed single-cell genomes). For the methods generating trees over samples, and not the clones, colored nodes represent samples. Blue nodes represent clones containing only normal cells, orange nodes represent clones containing only cancer cells, and brown nodes represent clones containing both normal and cancer cells. Text within the nodes indicates the identification number of the assigned sample cell(s) to the corresponding clone. White nodes represent nodes with no observed sample.