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Optimizing mitochondrial maintenance in extended neuronal projections

Fig 3

Comparison of mitochondrial maintenance models for matched parameter values.

(a) Steady-state normalized mitochondrial health averaged over all demand regions is computed with the CoG model (solid lines) and the SS model (dashed lines) as a function of the fraction of stopped mitochondria (fs) for three different values of the effective protein stopping probability . (b) Corresponding plots of the normalized health in the most distal demand site, for both models. All values are computed with M = 1500, , and n = 30.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1009073.g003