Examining the dynamics of Epstein-Barr virus shedding in the tonsils and the impact of HIV-1 coinfection on daily saliva viral loads
Fig 4
The impact of varying b and θ on model simulation trajectories.
Model simulations for different pairings of values for parameters b and θ are shown (units of cell day−1 and day−1 respectively). Simulations reproduce the stochastic nature of the data and are able to capture a wide variety of EBV shedding traits. For all simulations, β = 50 day−1, f = 0.1 day−1cell−1, α = 200 cells, δ = 0.1 day−1, p = 104 virions day−1 ml−1 cell−1, and c = 6 day−1. The grey horizontal line represents the qPCR threshold of detection. All simulated viral loads below this threshold were set to zero to match with participant data.