Inclusion of maintenance energy improves the intracellular flux predictions of CHO
Fig 2
Estimated mATP values and their effect on flux prediction accuracy.
(A) Computationally estimated mATP values for different datasets with two biomass equations. (B) R2 values from linear fits of experimental and predicted intracellular fluxes without (-mATP) or with mATP (+mATP) as constraint. The legend indicates the publication and the used CHO cell line (if the information was available). Empty symbols indicate non-producers.