Performance assessment of sample-specific network control methods for bulk and single-cell biological data analysis
Fig 2
The evaluation of structural network control methods by simulation of biological networks.
The goal is to evaluate the control efficiency by synthetically achieving control of the networked nonlinear Lorentz oscillator system towards desired attractors on two biological directed protein interaction networks from different resources (i.e. Network-1 and Network-2). (A-B) Desired attractor (8,484, 8.484, 27); (C-D) Desired attractor (-8,484, -8.484, 27); (E-F) Desired attractor (0, 0, 0). The efficiency of a given network is measured by the average value for different tolerance errors from 0.1 to 1.