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On the effect of phylogenetic correlations in coevolution-based contact prediction in proteins

Fig 6

z-scores of couplings derived from the natural MSA, as compared to the distribution of couplings derived from Null model II.

For each residue pair (i, j), we calculate the z-score for the DCA score derived from natural data as compared to 50 realizations of Null model II. Panel A shows the data for the dataset DS2 of large MSA, Panel B for DS3 of small-intermediate MSA.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1008957.g006