On the effect of phylogenetic correlations in coevolution-based contact prediction in proteins
Fig 4
Histogram of DCA scores derived from natural sequence data (Panel A) and Null model II (Panel B) for residue-residue contacts and non-contacts.
For the protein families in DS2, we show the histograms of DCA coupling scores (APC corrected Frobenius norm of couplings), separated for contacts and non-contacts (defined using the representative protein structures in Table B in S1 Text). Only pairs with linear separation |i − j| > 4 along the chain are taken into account.