Efficient representations of tumor diversity with paired DNA-RNA aberrations
Table 1
For each of the six tissues, one example of a common STP λ = (g ⇒ g′) is shown. P(DNA&RNA) is our sample-based estimate of the probability that λ is an aberrant pair, namely, the fraction of samples of the indicated tissue for which the source gene g is DNA-aberrant and the target gene g′ is RNA-aberrant. Similarly, P(DNA) (respectively, P(RNA)) is the fraction of samples for which g is DNA-aberrant (resp., g′ is RNA-aberrant), and P(RNA|DNA) is the (estimated) conditional probability that g′ is RNA-aberrant given g is DNA-aberrant.