Efficient representations of tumor diversity with paired DNA-RNA aberrations
Fig 6
Coding tree for breast ER status at target level.
For Breast tumor samples, a weighted coding tree T with depth d = 5 is constructed using one covering at target level. At each internal node, a sample is sent to the left if the indicated two genes at the node are both RNA aberrant with some aberrant source, whereas it is sent to the right otherwise. Sample counts for each terminal nodes are indicated and highlighted using a green palette. The two histograms at the bottom show the sample distribution at the 32 terminal nodes for the ER negative and ER positive sub-populations.