Efficient representations of tumor diversity with paired DNA-RNA aberrations
Fig 4
Comparison of one covering network for luminal breast cancer subtypes.
The probabilities of DNA aberration (with targets) and RNA aberration (with sources) over the Luminal A and Luminal B populations of breast cancer are depicted by the size of each node in the network, which corresponds to one possible covering. The red arrows indicate some sources and target genes that have noticeable differences in the respective probabilities between the two luminal subtypes (e.g., TP53, CHEK1, PIK3CA, and TOP2A, also see Table 6).