Efficient representations of tumor diversity with paired DNA-RNA aberrations
Fig 3
Core set across tissues at source level.
There are 18 source genes which appear in the core set of at least two tissues. For instance, gene TP53 is a core gene for all six tissues, and genes PTEN and PIK3CA are core genes for three tissues. The color in the heatmap on the left represents the probability that the corresponding source gene is DNA-aberrant and there exists an RNA-aberrant target gene (thereby forming an aberrant source-target pair). On the right, black marks indicate the membership of each gene to the corresponding core set for each tumor type.