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The metastable brain associated with autistic-like traits of typically developing individuals

Fig 4

Transition dynamics among delta-alpha PAC states in a lower-dimensional space.

(A to E) Representative delta-alpha PAC dynamics for an individual with higher attention-related AQ subscores (refer to Fig 3A to 3D(i)). (F to J) Representative dynamics for an individual with lower scores (refer to Fig 3D(ii)). (A, F) The trajectory of labeled signals in a plane. (B, G) The corresponding bivariate histograms. (C, H) Surrogate data testing under a condition of d = 2. (D, I) The resulting delta-alpha PAC states (represented by the mean PAC strengths). (E, J) Transitions between the identified PAC states. Surrogate data testing was applied to the density of points indicated by the red circles in panels B and G and the red lines in panels C and H, and the null hypothesis H0 in condition d = 2 was rejected (C and H). The delta-alpha PAC dynamics tended to stay in a state for a longer time and to visit a lower number of states in individuals with higher AQ subscores for attention to detail and attention switching (compare E with J). The colors in panels A, E, F, and J indicate distinct states, as depicted in D and I.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1008929.g004