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Building blocks and blueprints for bacterial autolysins

Fig 3

Common gram negative lytic enzyme architectures.

In each graph, the nodes indicate domains (along with the N terminus and C terminus), with size reflecting frequency within the organism’s clustered proteins and empty circles for domains with no representation in that species. The edges represent connections within a single protein, with edge shading and thickness representing relative frequency. Note that there are some self-edges (e.g., LysM loops back to itself), indicating a repeated domain. A path from Nterm through one or more domains to Cterm thus represents a protein, though not all such proteins have been observed in LEDGOs (see text).

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1008889.g003