Using the antibody-antigen binding interface to train image-based deep neural networks for antibody-epitope classification
Table 7
Classification of 30 Abs that bind exclusively to one out three possible epitopes.
Two binding sites recognized by Abs from Set1 (ADI-15734 competitors) and Set2 (ADI-15878 competitors) are located at the base of the EBOV-GP trimer, and the third epitope recognized by Abs from Set3 (ADI-15974 competitors) is located at HR2/MPER region. All DNN models are based on evaluating fingerprint images based on the charge coloring code.