Using the antibody-antigen binding interface to train image-based deep neural networks for antibody-epitope classification
Fig 4
Set of four antibodies associated with one family lineage.
(A) The graph highlights the amino acid substitutions in the heavy chain CDR3 region of the Abs with respect to the germline gene. Abs ADI-15912 and ADI-15843 share the same CDR3 sequence. (B) Each column shows three fingerprints for each Ab of the family showing how the amino acid substitutions listed in (A), and conformational changes in the models affect the fingerprints.