Hypoxic pulmonary vasoconstriction as a regulator of alveolar-capillary oxygen flux: A computational model of ventilation-perfusion matching
Fig 4
Whole-organ pressure-flow relationships.
Discrete data points are taken from isolated-perfused-ventilated lung experiments performed in Molthen et al. [50] and Chlopicki et al. [20]. Simulations are run under Zone 3 conditions (venous outlet pressure (7 mmHg) > alveolar pressure (6 mmHg)). The model simulation curves that are near the 95% N2 (Chlopicki) data point were run with T* = 0.8, and the curves near the Papaverine (Molthen) data points were run with T* = 0.5.