Hypoxic pulmonary vasoconstriction as a regulator of alveolar-capillary oxygen flux: A computational model of ventilation-perfusion matching
Fig 3
Morphometrically realistic pulmonary vascular networks.
(A,B,C) Synthetic population of rat lungs. Blue dots are the finite-element mesh points made by Polymesher [34], the cyan circles denote the root node for each network, the black lines represent the network topology, and the red squares denote the network terminals. The black scale bar is 3000 μm. All networks were made with 1,000 nodes and Δg set to 50 μm. Note that the radius of each vessel is not plotted to size. The total area spanned by each finite element mesh is the same. (D, E) Comparison of our network geometries to measured diameters and lengths as a function of diameter-defined Strahler orders from silicone-elastometer casts of rat pulmonary arterial trees in Jiang et al. [35].